Education
Postdoctoral Research Fellow
University of Michigan, Ann Arbor, Michigan
Ph.D., Toxicology
University of Michigan, Ann Arbor, Michigan
B.A. Chemistry
Kent State University, Kent, Ohio
Experience
BA Thor Consulting, LLC, Mattawan, Michigan
Owner/Principal
November 2023 to Present
Frontage Laboratories, Chicago, Illinois
Vice President, Scientific Operations
January 2021 to November 2023
Experimur, Chicago, Illinois
Assistant Vice President, Developmental and Reproductive Toxicology (DART) & Infant Nutrition
April 2015 to December 2021
MPI Research, Mattawan, Michigan
Director, Infant Nutritional Sciences
2014-2015
Principal Study Director, DART
2013-2015
Senior Study Director, DART
2006-2013
Dow Chemical Company, Midland, Michigan
Lead Scientist, DART
2004-2006
Charles River Laboratories, Spencerville, Ohio (Springborn Laboratories, acquired 2002)
Director, DART
2001-2004
Manager, DART
1998-2001
Senior Study Director, DART
1997-1998
Professional Associations
Round Table of Toxicology Consultants (RTC)
Society of Toxicology (SOT)
Society for Birth Defects and Prevention (BDRP, formerly the Teratology Society)
American College of Toxicology (ACT)
Publications
1. Mermelstein N (2017) Starting Babies Off Right, based on IFT 2016 symposium titled
Regulatory and Safety Evaluation of Ingredients with presenters Carrie L Assar (FDA),
Claire L Kruger (Chromadex), Roger A. Clemens (University of Southern California),
and Bjorn A Thorsrud (Experimur). Food Safety & Quality, Food Technology, Institute
of Food Technologists (IFT) Newsletter, July, Vol 71, No. 7.
2. Kruger C, Zhou Y, Thorsrud BA, Morel-Despeisse F, Chappuis E (2017) Safety
Evaluation of α-Galacto-Oligosaccharides for Use in Infant Formulas Investigated in
Neonatal Piglets. Toxicology Research and Application, 1:1-10.
3. Food and Agriculture Organization (FAO) of the United Nations and World Health
Organization (WHO). (2015) Safety Evaluation of Certain Food Additives. Citations by
Thorsrud BA as Study Director on piglet studies with carrageenan (2013) and octenyl
succinic acid (2012). Prepared by the Joint Expert Committee on Food Additive (JECFA)
at the 79 th Meeting, WHO Food Additives Series: 70, Geneva, Switzerland.
4. Zeigler BM, Cameron M, Nelson K, Bailey K, Weiner, ML, Mahadevan B, Thorsrud
BA (2015) The Development and Validation of Methods for Evaluating the Immune
System in Preweaning Piglets. Food and Chemical Toxicology, 84:197-207.
5. Choi SH, Lynch BS, Baldwin N, Dakoulas EW, Roy S, Moore C, Thorsrud BA, and
Röhrig CH (2015) Safety Evaluation of L-Fucose in Sprague Dawley Rats. Regul
Toxicol Pharmacol, 72:39-48.
6. Weiner ML, Ferguson HE, Thorsrud BA, Nelson KG, Blakemore WR, Zeigler B,
Cameron MJ, Brant A, Cochrane L, Pellerin M, Mahadevan B (2015) An infant formula
toxicity and toxicokinetic feeding study on carrageenan in preweaning piglets with
special attention to the immune system and gastrointestinal tract. Food and Chemical
Toxicology, 77:120-131.
7. Hanlon P and Thorsrud BA (2014) A 3-Week Pre-Clinical Study of 2’-Fucosyllactose in
Farm Piglets. Food and Chemical Toxicology, 14:343-348.
8. Mahadevan B, Thorsrud BA, Brorby GP, and Ferguson H (2014) A 3-Week Dietary
Safety Study of Octenyl Succinic Anhydride (OSA)-Modified Starch in Neonatal Farm
Piglets. Food and Chemical Toxicology, 72: 83-89.
9. Dahms I, Thorsrud BA, Bailey E, and Salem Jr N (2014) DHASCO-B and DHASCO:
A 3-Week Dietary Bioequivalence Study in Preweaning Farm Piglets. Food and
Chemical Toxicology, Mar, 65: 43-51.
10. Choi SH, Baldwin N, Waggner II VO, Roy S, Rose J, Thorsrud BA, Phothirath P, and
Röhrig CH (2014) Safety Evaluation of Sialic Acid in Sprague-Dawley Rats. Regul
Toxicol Pharmacol, Aug 8; 70(2): 482-491.
11. Thorsrud BA, Faqi AS, Beck MJ, and Morford LL (2012). Juvenile toxicity testing to
support clinical trials in the pediatric population. A Comprehensive Guide to Toxicology
in Preclinical Drug Development. Ali S Faqi editor, Elsevier, 15:383-393.
12. Schardein JL, Birch R, Hesley R and Thorsrud B (2012). Multigeneration reproductive
study of hydroxyprogesterone caproate (HPC) in the rat: Laboratory results and clinical
significance. Birth Defects Research (Part B) 95: 160-174.
13. Thorsrud, BA and Faqi AS (2011). Developmental and reproductive toxicity of TCDD,
lead and mercury. Encyclopedia of Environmental Health, Volume 2. Jerome Nriagu
editor-in-chief. Elsevier, UK.
14. Thorsrud BA, Dugard P, Zablotny C and Carney EW (2006). Developmental toxicity
studies in CD rats following inhalational exposure to trichloroethylene and
perchlorethylene. Birth Defects Research B Dev Tox Reprod Toxicol, 77(5):405-412.
15. Meyer KE, Hawks RJ, Serbinova EA, Marafino B, Merriman TN, Thorsrud BA, Learn,
DB, Frantz SW, Secrest JT and Gundel RH (2004). Nonclinical safety evaluation of
XMP.629, a novel peptide for acne treatment. International Congress of Toxicology,
Tampere, Finland.
16. Marty MS, Chapin RE, Parks LG, and Thorsrud BA (2003). Development and
maturation of the male reproductive system. Birth Defects Research (Part B) 68:125-136.
17. Clark HA, Barker SLR, Brasuel M, Miller MT, Monson E, Parus S, Shi ZY, Song A,
Thorsrud B, Kopelman R, Ade A, Meixner W, Athey B, Hoyer M, Hill D, Lightle R,
and Philbert MA (1998). Subcellular optochemical nanobiosensors: probes encapsulated
by biologically localized embedding (PEBBLEs). Sensors and Actuators B-Chemical 51,
18. Tan WH, Thorsrud BA, Harris C, and Kopelman R (1998). Real time pH measurements
in the intact rat conceptus using ultramicrofiber-optic sensors. In “Polymers in Sensors”,
Vol. 690, pp. 266-272. American Chemical Society, Washington D.C.
19. Barker LR, Thorsrud BA, and Kopelman R (1997). Nitrite and chloride selective
fluorescent nano-optodes and in vitro applications to rat conceptus. Analytical
Chemistry.
20. Harris C, Lee E, Hiranruengchok R, McNutt TL, Larson SJ, Akeila S, and Thorsrud BA
(1996). Characteristics of glutathione redox and antioxidant status in post implantation rat
embryos: response to oxidative stress. Toxicologist 30:2.
21. Thorsrud BA and Harris C (1995). Real time, micro-fiberoptic redox fluorometry:
Modulation of the pyridine nucleotide status of the organogenesis-stage rat visceral yolk
sac with cyanide and alloxan. Toxicology and Applied Pharmacy, 135:237-245.
22. Tan W, Shi Z, Harris C, Kopelman R and Thorsrud B (1994). Ultra micro-fiberoptic
chemical sensors and real time biochemical measurements on single rat embryos.
Bioanalytical Chemistry Mini-Conference, Microbioanalytical Chemistry. Pittsburgh
conference of Analytical Chemistry and Applied Spectroscopy, Pittsburgh, PA.
23. Tan W, Shi Z, Thorsrud B, Harris C and Kopelman R (1994). Near field fiber optic
chemical sensors and biological applications. Optical Tools for Manufacturing and
Advanced Automation. International Society of Optical Engineering, 2068:59-68.
24. Thorsrud BA and Harris C (1993). Real Time Micro-Fiberoptic Monitoring of
Endogenous Fluorescence in the Rat Conceptus. Teratology 48(4):343-353.
25. Tan W, Birnbaum D, Harris C, Merlin R, Orr B, Shi Z, Smith S, Thorsrud B and
Kopelman R (1993). Near field optics: Chemical sensors, photon supertips and
subwavelength spectroscopy. (eds. Masuhara, H. et. al.) Microchemistry, Academic
Press, Netherlands. Joint International Symposium on Spectroscopy and Chemistry in
Small Domains, Brussels, Belgium.
26. Smith S, Monson E, Merritt G, Tan W, Birnbaum D, Shi Z, Thorsrud B, Harris C, Grahn
H, Merlin R, Orr B, Langmore J and Kopelman R (1993). Tip/sample interactions,
contrast and near-field microscopy of biological and solid-state samples. Scanning Probe
Microscopies, International Society for Optical Engineering, 1855(13):81-92.
Awards and Honors
Highest Publisher Recognition Award, MPI Research, February 28, 2015.
High Publisher Recognition Award, MPI Research, March 2, 2013.
Judge at the Annual Michigan State University Undergraduate Research and Arts Forum Poster
and Oral Competition on behalf of the Michigan Chapter of the Society of Toxicology, East
Lansing, 2012 and 2013.
Judge at the Graduate Student Poster Competition of the Michigan Chapter of the Society of
Toxicology, Fall Meeting, Ann Arbor, Michigan, 2008; Fall Meeting, East Lansing, Michigan,
2009; Fall Meeting, East Lansing, Michigan, 2010, Fall Meeting, Ann Arbor, 2012.
ILSI Publication (Marty et al., 2003) cited in Guidance for Industry: Nonclinical Safety
Evaluation of Pediatric Drug Products, FDA, CDER, February 2006.
Adjunct Professor, Ohio State University, School of Public Health, Columbus, Ohio (2001 to
2004).
Judge at the Graduate Student Poster Competition at the Ohio Valley Society of Toxicology
Meeting, Dayton, Ohio, 1998.
Member of Ph.D. Dissertation Committee, Department of Environmental & Industrial Health,
School of Public Health, University of Michigan, Ann Arbor, Michigan, 1996-1998.
One Term Dissertation Fellowship, Rackham School of Graduate Studies, University of
Michigan, Ann Arbor, Michigan, 1995.
Founder and President of the University of Michigan Toxicology Student Association (UMTSA),
Department of Environmental & Industrial Health, School of Public Health, University of
Michigan, Ann Arbor, Michigan, 1992-1993.
Student Representative to the Toxicology Program Faculty, Department of Environmental &
Industrial Health, School of Public Health, University of Michigan, Ann Arbor, Michigan, 1992-
1993.
Best Graduate Student Poster Presentation, presented by the Midwest Teratology Association,
Teratology Society Meeting, Boca Raton, Florida, 1992.
Presentations
1. Chappuis E, Le Fresne S, Thorsrud, BA (2017) Plant-Based Galacto-Oligosaccharides
Support Adequate Growth and Have Prebiotic Properties in Pre-Weanling Piglets.
International Conference on Nutrition and Growth, Amsterdam, the Netherlands.
2. Blakemore WR, Brant A, Chochrane L, Pellerin M, Thorsrud B, Weiner ML, Ferguson
H, Frantz B (2014) Safety of Carrageenan in Infant Formula: A 4-Week Toxicokinetic
Evaluation in Preweaning Piglets. Society of Toxicology Meeting, Phoenix, Arizona.
3. Zeigler B, Cameron, M, Nelson K, Thorsrud B, Weiner ML, Ferguson H, Frantz B
(2014) Safety of Carrageenan in Infant Formula: A 4-Week Study of the Potential
Immune System Effects in Preweaning Piglets. Society of Toxicology Meeting, Phoenix,
Arizona.
4. Weiner ML, Ferguson H, Thorsrud B, Nelson K, Blakemore WR, Frantz, B (2014)
Safety of Carrageenan in Infant Formula: A 4-Week Toxicity Study in Preweaning
Piglets. Society of Toxicology Meeting, Phoenix, Arizona.
5. Thorsrud B, Cameron, M, Zeigler B, Nelson K, McKim Jr JM, Weiner ML, Ferguson H,
Frantz B, Blakemore WR (2014) The Development and Validation of Methods for
Evaluating the Immune System in Preweaning Piglets. Society of Toxicology Meeting,
Phoenix, Arizona.
6. Mahadewan, B, Thorsrud BA, Ferguson H (2014) A 3-Week Dietary Toxicity Study of
Octenyl Succinic Anhydride (OSA) – Modified Starch in Preweaning Farm Piglets.
Society of Toxicology Meeting, Phoenix, Arizona.
7. Prater J, Sweet J, Tawoda L, Thorsrud B (2013) Endoscopic Placement of a
Percutaneous Endoscopic Gastrostomy Feeding Tube in Juvenile Swine. Received
Michael DeLeo Award. Academy of Surgical Research Meeting, Las Vegas, Nevada.
8. Gasper C, Thorsrud B, Cao L, Chen J, Wong L, Der K, Ma J, Ahene A, Meyer K (2013)
Developmental and Reproductive Toxicology Studies in Sprague Dawley Rats with
Gevokizumab, a Novel Monoclonal Antibody Targeting IL-1 Beta. Society of
Toxicology Meeting, San Antonio, Texas.
9. Thorsrud BA, Aulbach AD and Faqi AS (2012). Neonatal Piglets as an Animal Model
to Evaluate Safety of new Ingredients in Infant Formula. Society of Toxicology Meeting,
San Francisco, California.
10. Schardein J, Birch R, Hesley R, Jofrion J, Gudeman J, Jozwiakowski M and Thorsrud B
(2012). A Multi-Generational Reproductive Toxicology (MGRT) Study in Rats Shows
No Evidence of a Safety Signal for Hydroxyprogesterone Caproate (HPC, Makena ® ,
17P). Society for Maternal Fetal Medicine Meeting, Dallas, Texas.
11. Gasper C, Thorsrud B, Ma J, Cao L, Der K, and Meyer K. (2011). A Study of Fertility
and Early Embryonic Development to Implantation in Sprague Dawley Rats with XOMA
052, a Novel Monoclonal Antibody Targeting IL-1 Beta. Society of Toxicology Meeting,
Washington DC.
12. Gasper C, Thorsrud B, Ma J, Chen J, Der K, and Meyer K (2011). A Developmental
Toxicity Study in Sprague Dawley Rats with XOMA 052, a Novel Monoclonal Antibody
Targeting IL-1 Beta. Society of Toxicology Meeting, Washington DC.
13. Thorsrud BA, Resendez JC, Faqi AS, Holdsworth DL and Baird TJ (2010). A
Comparative Evaluation of Cardiac Parameters of the Electrocardiogram (ECG) in
Juvenile Beagle Dogs and Non-Human Primates. Teratology Society Meeting, Louisville,
Kentucky.
14. Thorsrud BA, Faqi AS, Holdsworth DL and Baird TJ (2010). Comparative Analysis of
Cardiac Rhythm and Quantitative Elements of the Electrocardiogram (ECG) in Juvenile
and Adult Beagle Dogs. Society of Toxicology Meeting, Salt Lake City, Utah.
15. Gasper C, Thorsrud B, Hawks R, Tibbits J and Meyer K (2006). XMP.629, A novel
antimicrobial peptidomimetic for the treatment of mild to moderate acne vulgaris:
Evaluation of potential developmental effects of XMP.629 in Sprague Dawley rats and
New Zealand White rabbits. Society of Toxicology Meeting, San Diego, California.
16. Kapp RW, Thorsrud BA, Moffatt WJ, and Lawton L (2003). A combined repeated dose
toxicity study and reproduction/development screening in Sprague-Dawley rats with
acetophenone (OECD Guideline No. 422). Society of Toxicology Meeting, Salt Lake
City, Utah.
17. Thorsrud BA, Tan W, Harris C and Kopelman R (1996). Real time monitoring of the
extraembryonic fluid pH in the organogenesis stage rat conceptus. Analytical and
Physical Chemistry Poster Session, University of Michigan, Ann Arbor, Michigan.
18. Harris C, Lee E, Hiranruengchok R, McNutt TL, Larsen SJV, Akella S, and Thorsrud
BA (1996). Characteristics of glutathione redox and antioxidant status in
postimplanatation rat embryos: response to oxidative stress. Society of Toxicology
Meeting, Anaheim, California.
19. Harris C, Kenneway E, Lee E, Larsen S and Thorsrud BA (1995). Formaldehyde
embryotoxicity in mouse conceptus grown in whole embryo culture. Society of
Toxicology Meeting, Baltimore, Maryland.
20. Thorsrud BA and Harris C (1994). The use of micro-fiberoptic biosensor to
fluorometrically monitor changes in the cellular redox status of the organogenesis-stage
rat visceral yolk sac during exposure to cyanide and alloxan. First Annual Toxicology
Research Symposium, Toxicology Program, University of Michigan, Ann Arbor,
Michigan.
21. Harris C, Tan W, Thorsrud BA, and Kopelman R (1994). Ultramicrofiberoptic pH
sensors for measurement of real time responses to chemical insult in intact,
organogenesis-stage rat conceptuses. Society of Toxicology Meeting, Dallas, Texas.
22. Tan W, Thorsrud BA, Harris C and Kopelman R (1993). Near-field optical biochemical
sensors and in vivo biochemical measurements on single rat conceptuses. Department of
Molecular Biophysics, University of Michigan, Ann Arbor, Michigan.
23. Thorsrud BA and Harris C (1992). Real time micro-fiberoptic monitoring of
endogenous fluorescence in the rat conceptus. Teratology Society Meeting, Boca Raton,
Florida.
24. Thorsrud BA and Harris C (1992). Real time micro-fiberoptic monitoring of
endogenous fluorescence in the rat conceptus during hypoxia. Reproductive Sciences
Program, University of Michigan, Ann Arbor, Michigan.
25. Thorsrud BA and Harris C (1991). The development and use of a micro-optical
spectrofluorometric technique for use with cultured whole rat conceptuses during
organogenesis. Reproductive Sciences Program, University of Michigan, Ann Arbor,
Michigan.
Patents
Optical Fiberless Sensors, US Patent Number 6,379,955. Fiberless optical sensors (plasticized
PVC, acrylamide or gold particles) are described having a size ranging from between
approximately 1 micrometer and 1 nanometer in diameter. The sensors comprise ionophores
useful for the detection of intracellular analytes. Inventors: Raoul Kopelman, Heather Clark,
Eric Monson, Stephen Parus, Martin Philbert, Bjorn Thorsrud. Original Assignee: Regents of the
University of Michigan, Ann Arbor, Michigan.
Optical Fiberless Sensors for Analyzing Cellular Analytes. US Patent No. 6,143,558. Fiberless
optical sensors (plasticized PVC, acrylamide or gold particles) are described having a size
ranging from between approximately 1 micrometer and 1 nanometer in diameter. The sensors
comprise ionophores useful for the detection of intracellular analytes. Inventors: Raoul
Kopelman, Heather Clark, Eric Monson, Stephen Parus, Martin Philbert, Bjorn Thorsrud.
Original Assignee: Regents of the University of Michigan, Ann Arbor, Michigan.
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